INT344420

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Context Info
Confidence 0.27
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.40
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Ltc4s) nuclear envelope (Ltc4s) lyase activity (Ltc4s)
endoplasmic reticulum (Ltc4s) nucleus (Ltc4s)
Anatomy Link Frequency
eosinophils 1
Ltc4s (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 14 99.72 Very High Very High Very High
Inflammation 19 5.00 Very Low Very Low Very Low
fibrosis 8 5.00 Very Low Very Low Very Low
chemokine 5 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Airway Remodeling 26 87.12 High High
Asthma 14 74.96 Quite High
Hypertrophy 1 71.36 Quite High
Fibrosis 9 23.36 Low Low
INFLAMMATION 20 5.00 Very Low Very Low Very Low
Rhinitis 12 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Occupational Lung Diseases 1 5.00 Very Low Very Low Very Low
Hypereosinophilic Syndrome 1 5.00 Very Low Very Low Very Low
Peripheral Arterial Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One possible explanation is that the increased numbers of eosinophils in the airway in Siglec-F deficient mice express increased levels of mediators that can influence mucus secretion including granule mediators (ECP, MBP)[29,30], lipid mediators (LTC4)[31], cytokines (IL-13)[31], or other at present unknown mediators.
Localization (secretion) of LTC4 in eosinophils associated with cytokine
1) Confidence 0.27 Published 2010 Journal Respir Res Section Body Doc Link PMC2988013 Disease Relevance 0.40 Pain Relevance 0.05

General Comments

This test has worked.

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