INT344613

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Context Info
Confidence 0.31
First Reported 2010
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.19
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CLTC) mitosis (CLTC) mitochondrion (CLTC)
vesicle-mediated transport (CLTC) structural molecule activity (CLTC) plasma membrane (CLTC)
Anatomy Link Frequency
neurons 2
cortex 2
CLTC (Homo sapiens)
Pain Link Frequency Relevance Heat
reflex sympathetic dystrophy 2 86.12 High High
Pain 7 70.36 Quite High
cva 5 58.04 Quite High
Central nervous system 6 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
intrathecal 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
tetrodotoxin 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nervous System Injury 3 90.48 High High
Hypersensitivity 12 88.64 High High
Complex Regional Pain Syndromes 2 86.12 High High
Rupture 16 83.04 Quite High
Dizziness 1 73.08 Quite High
Pain 7 70.36 Quite High
Lacerations 1 62.00 Quite High
Staphylococcus Infection 1 60.88 Quite High
Ecchymosis 2 60.12 Quite High
Contusions 1 58.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
85.8% of those receiving a single injection developed anti-CHC antibodies, with 100% of patients testing positive following three injections.
Negative_regulation (developed) of Gene_expression (antibodies) of anti-CHC
1) Confidence 0.31 Published 2010 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2988615 Disease Relevance 1.19 Pain Relevance 0.37
Hence, the TP25.99 antibody likely recognized a large number of MHCI-HC proteins expressed on V1 neurons, including the ones targeted at the mRNA level by in situ hybridization riboprobe.
Negative_regulation (number) of Gene_expression (expressed) of MHCI-HC in neurons
2) Confidence 0.03 Published 2011 Journal Behav Brain Funct Section Body Doc Link PMC3023691 Disease Relevance 0 Pain Relevance 0
However, in situ hybridization revealed a strong expression of MHCI-HC throughout the visual cortex.
Negative_regulation (revealed) of Gene_expression (expression) of MHCI-HC in cortex
3) Confidence 0.03 Published 2011 Journal Behav Brain Funct Section Body Doc Link PMC3023691 Disease Relevance 0 Pain Relevance 0

General Comments

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