INT344706

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.39
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Abca1) Golgi apparatus (Abca1) intracellular (Abca1)
DNA binding (Nr1h2) cytoplasm (Nr1h2) nucleus (Nr1h2)
Anatomy Link Frequency
macrophage 2
liver 1
Nr1h2 (Mus musculus)
Abca1 (Mus musculus)
Pain Link Frequency Relevance Heat
Bile 15 65.20 Quite High
agonist 75 5.00 Very Low Very Low Very Low
Inflammation 33 5.00 Very Low Very Low Very Low
aspirin 15 5.00 Very Low Very Low Very Low
antagonist 12 5.00 Very Low Very Low Very Low
Angina 9 5.00 Very Low Very Low Very Low
tolerance 9 5.00 Very Low Very Low Very Low
imagery 6 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 900 99.40 Very High Very High Very High
Apoptosis 12 68.12 Quite High
Death 30 67.60 Quite High
Atherosclerosis 168 61.84 Quite High
Coronary Heart Disease 210 5.00 Very Low Very Low Very Low
Myocardial Infarction 66 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 60 5.00 Very Low Very Low Very Low
Hypoalphalipoproteinemias 48 5.00 Very Low Very Low Very Low
Metabolic Syndrome 36 5.00 Very Low Very Low Very Low
Diabetes Mellitus 36 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The efflux occurs under the influence of LXR-alpa and LXR-beta that regulates the macrophage receptors ABCA-1, ABCG-1 and SR B-1, and facilitate lipidation of apo A-1 and HDL.
LXR Regulation (regulates) of ABCA-1 in macrophage associated with disorder of lipid metabolism
1) Confidence 0.03 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2988622 Disease Relevance 0.73 Pain Relevance 0.06
The efflux occurs under the influence of LXR-alpa and LXR-beta that regulates the macrophage receptors ABCA-1, ABCG-1 and SR B-1, and facilitate lipidation of apo A-1 and HDL.
LXR Regulation (regulates) of ABCA-1 in macrophage associated with disorder of lipid metabolism
2) Confidence 0.03 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2988622 Disease Relevance 0.79 Pain Relevance 0.06
The ABCA-1 and ABCG-1 receptors are regulated by the nuclear liver-X-receptors-alpha (LXR-alpha) and LXR-beta.
LXR Regulation (regulated) of ABCA-1 in liver
3) Confidence 0.03 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2988622 Disease Relevance 0.87 Pain Relevance 0

General Comments

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