INT344709

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Context Info
Confidence 0.32
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.74
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Niacr1) plasma membrane (Niacr1) signal transducer activity (Niacr1)
Niacr1 (Mus musculus)
Hdl1 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 8 96.96 Very High Very High Very High
aspirin 10 93.72 High High
agonist 50 77.84 Quite High
alcohol 2 69.32 Quite High
Inflammation 22 61.60 Quite High
tolerance 6 38.00 Quite Low
Bile 10 5.00 Very Low Very Low Very Low
Angina 6 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 600 100.00 Very High Very High Very High
Coronary Heart Disease 140 98.76 Very High Very High Very High
Dyslipidemia /

Combined Dyslipidemia

18 98.44 Very High Very High Very High
Increased Venous Pressure Under Development 40 97.12 Very High Very High Very High
Pruritus 2 87.76 High High
Metabolic Syndrome 24 80.16 Quite High
INFLAMMATION 22 61.60 Quite High
Myocardial Infarction 44 19.12 Low Low
Atherosclerosis 112 5.00 Very Low Very Low Very Low
Hypoalphalipoproteinemias 32 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
While statin, niacin, and fibrate therapies have been demonstrated to increase HDL to a varying extent and improve cardiovascular outcomes, a number of newer therapeutic agents have now appeared on the horizon that hold promise for raising HDL.
niacin Positive_regulation (increase) of HDL associated with disorder of lipid metabolism
1) Confidence 0.32 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2988622 Disease Relevance 1.33 Pain Relevance 0.14
Despite its ability to significantly increase the HDL levels, the use of niacin in the treatment of low HDL has been limited due to its side-effect of flushing.
niacin Positive_regulation (increase) of HDL associated with increased venous pressure under development and disorder of lipid metabolism
2) Confidence 0.23 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2988622 Disease Relevance 1.32 Pain Relevance 0.32

General Comments

This test has worked.

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