INT344711

Context Info Confidence 0.03 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 1.67 Pain Relevance 0

endosome (Abcg1) transport (Abcg1) Golgi apparatus (Abcg1) intracellular (Abcg1) DNA binding (Nr1h3) cytoplasm (Nr1h3)

Anatomy Link Frequency liver 2 Nr1h3 (Mus musculus) Abcg1 (Mus musculus)

Pain Link Frequency Relevance Heat Bile 10 43.68 agonist 50 5.00 Inflammation 22 5.00 aspirin 10 5.00 antagonist 8 5.00 Angina 6 5.00 tolerance 6 5.00 imagery 4 5.00 cytokine 2 5.00 adenocard 2 5.00

Disease Link Frequency Relevance Heat Disorder Of Lipid Metabolism 600 98.96 Apoptosis 8 67.68 Death 20 67.16 Atherosclerosis 112 61.40 Coronary Heart Disease 140 5.00 Myocardial Infarction 44 5.00 Increased Venous Pressure Under Development 40 5.00 Hypoalphalipoproteinemias 32 5.00 Metabolic Syndrome 24 5.00 Diabetes Mellitus 24 5.00

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Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The ABCA-1 and ABCG-1 receptors are regulated by the nuclear liver-X-receptors-alpha (LXR-alpha) and LXR-beta.

nuclear liver-X-receptors-alpha Regulation (regulated) of ABCG-1 in liver

1) Confidence 0.03 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2988622 Disease Relevance 0.81 Pain Relevance 0

The ABCA-1 and ABCG-1 receptors are regulated by the nuclear liver-X-receptors-alpha (LXR-alpha) and LXR-beta.

LXR-alpha Regulation (regulated) of ABCG-1 in liver

2) Confidence 0.03 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2988622 Disease Relevance 0.86 Pain Relevance 0

General Comments

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