INT344715

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.83
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Ppara, Pltp) transport (Pltp) extracellular region (Pltp)
nucleus (Ppara) DNA binding (Ppara) lipid metabolic process (Ppara)
Anatomy Link Frequency
bile 3
Ppara (Mus musculus)
Pltp (Mus musculus)
Pain Link Frequency Relevance Heat
Bile 5 98.90 Very High Very High Very High
antagonist 4 92.88 High High
agonist 25 87.80 High High
Inflammation 11 61.52 Quite High
aspirin 5 5.00 Very Low Very Low Very Low
Angina 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 300 100.00 Very High Very High Very High
Atherosclerosis 56 69.36 Quite High
INFLAMMATION 11 61.52 Quite High
Coronary Heart Disease 70 38.00 Quite Low
Myocardial Infarction 22 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 20 5.00 Very Low Very Low Very Low
Hypoalphalipoproteinemias 16 5.00 Very Low Very Low Very Low
Metabolic Syndrome 12 5.00 Very Low Very Low Very Low
Diabetes Mellitus 12 5.00 Very Low Very Low Very Low
Death 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
FXR participates in the regulation of bile acid synthesis, conjugation, and transport.62 It also enhances the expression of one of the enzymes, phospholipid transfer protein, involved in HDL formation, and lowers TG levels by inducing PPAR-?
Positive_regulation (inducing) of PPAR in bile Positive_regulation (enhances) of Gene_expression (expression) of phospholipid transfer protein in bile associated with bile and disorder of lipid metabolism
1) Confidence 0.02 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2988622 Disease Relevance 0.83 Pain Relevance 0.28

General Comments

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