INT344720

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Context Info
Confidence 0.17
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.13
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Niacr1) plasma membrane (Niacr1) signal transducer activity (Niacr1)
Anatomy Link Frequency
liver 2
Niacr1 (Mus musculus)
Hdl1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 25 42.40 Quite Low
Inflammation 11 5.00 Very Low Very Low Very Low
aspirin 5 5.00 Very Low Very Low Very Low
Bile 5 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Angina 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 300 100.00 Very High Very High Very High
Obesity 1 80.64 Quite High
Rupture 1 69.08 Quite High
Atherosclerotic Plaque 1 67.44 Quite High
Liver Disease 2 57.28 Quite High
Anaphylaxis 1 56.52 Quite High
Diabetes Mellitus 12 56.40 Quite High
Atherosclerosis 56 45.28 Quite Low
Congenital Anomalies 5 40.84 Quite Low
Myocardial Infarction 22 34.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Niacin raises serum HDL levels by decreasing HDL catabolism in the liver by down-regulating the expression of the F1 moiety of F1F0 ATP synthetase, a holoparticle HDL receptor.
Niacin Negative_regulation (decreasing) of HDL Binding (catabolism) of in liver associated with disorder of lipid metabolism
1) Confidence 0.17 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2988622 Disease Relevance 1.13 Pain Relevance 0

General Comments

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