INT344746

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Context Info
Confidence 0.19
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.75
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (ABAT) lyase activity (GAD1) plasma membrane (GAD1)
intracellular (GAD1)
Anatomy Link Frequency
epithelium 2
GAD1 (Homo sapiens)
ABAT (Homo sapiens)
Pain Link Frequency Relevance Heat
gABA 59 100.00 Very High Very High Very High
GABAergic 46 97.04 Very High Very High Very High
Neurotransmitter 4 49.12 Quite Low
Central nervous system 3 46.40 Quite Low
Glutamate 5 39.28 Quite Low
Nicotine 9 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
GABA receptor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nicotine Addiction 68 98.90 Very High Very High Very High
Asthma 4 79.20 Quite High
Pulmonary Disease 2 62.60 Quite High
Generalized Anxiety Disorder 5 5.00 Very Low Very Low Very Low
Metaplasia 3 5.00 Very Low Very Low Very Low
Hyperplasia 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Sleep Disorders 1 5.00 Very Low Very Low Very Low
Adenocarcinoma 1 5.00 Very Low Very Low Very Low
Nervous System Malformation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Assessment of our database of airway epithelial gene expression generated by microarrays showed that, while many of the GABAergic system genes are expressed in the human large and small airway epithelium, cigarette smoking is associated with changes in gene expression only of GAD67, a gene controlling the synthesis of GABA [2].
GAD67 Regulation (controlling) of Gene_expression (synthesis) of GABA in epithelium associated with gaba, nicotine addiction and gabaergic
1) Confidence 0.19 Published 2010 Journal Respir Res Section Body Doc Link PMC2988726 Disease Relevance 0.75 Pain Relevance 0.23

General Comments

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