INT34476

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Context Info
Confidence 0.34
First Reported 1987
Last Reported 2002
Negated 2
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.71
Pain Relevance 3.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cck) extracellular region (Cck)
Cck (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Cholecystokinin 8 100.00 Very High Very High Very High
substance P 3 100.00 Very High Very High Very High
Dynorphin 2 100.00 Very High Very High Very High
Endep 7 99.82 Very High Very High Very High
Morphine 8 99.20 Very High Very High Very High
Enkephalin 13 98.32 Very High Very High Very High
withdrawal 1 98.32 Very High Very High Very High
cerebral cortex 2 97.00 Very High Very High Very High
Central grey 1 96.24 Very High Very High Very High
Physical dependence 1 91.68 High High
Disease Link Frequency Relevance Heat
Aging 4 99.98 Very High Very High Very High
Opiate Addiction 2 98.68 Very High Very High Very High
Urological Neuroanatomy 1 96.24 Very High Very High Very High
Drug Dependence 2 91.68 High High
Morphine Dependence 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Chronic treatment with amoxapine or amitriptyline did not affect the levels of dynorphin, substance P and cholecystokinin, but markedly enhanced the levels of leu-enkephalin in the three structures examined.
Neg (not) Regulation (affect) of Neg (not) Regulation (affect) of cholecystokinin associated with dynorphin, enkephalin, cholecystokinin, endep and substance p
1) Confidence 0.34 Published 1987 Journal Neuropharmacology Section Abstract Doc Link 3037421 Disease Relevance 0 Pain Relevance 1.69
Aging modified the haloperidol effect on beta-end level in AL and CCK level in NIL as the effect was only observed in young rats. 6.
Regulation (modified) of Regulation (effect) of CCK associated with aging
2) Confidence 0.24 Published 1995 Journal Prog. Neuropsychopharmacol. Biol. Psychiatry Section Abstract Doc Link 8787040 Disease Relevance 0.27 Pain Relevance 0.15
No change in CCK immunoreactivity occurred in these conditions.
Neg (No) Regulation (change) of Neg (No) Regulation (immunoreactivity) of CCK associated with cholecystokinin
3) Confidence 0.23 Published 2002 Journal J. Neurosci. Section Abstract Doc Link 11826132 Disease Relevance 0.44 Pain Relevance 1.94

General Comments

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