INT344781

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Context Info
Confidence 0.28
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.55
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Tgm2) mitochondrion (Tgm2) proteinaceous extracellular matrix (Tgm2)
plasma membrane (Tgm2) transferase activity, transferring acyl groups (Tgm2) cytoplasm (Tgm2)
Anatomy Link Frequency
apoptotic cell 2
Tgm2 (Mus musculus)
Pain Link Frequency Relevance Heat
Arthritis 12 89.52 High High
cytokine 45 68.24 Quite High
Inflammatory response 3 66.40 Quite High
metalloproteinase 93 63.76 Quite High
Inflammation 30 58.80 Quite High
Analgesic 6 57.44 Quite High
rheumatoid arthritis 21 5.00 Very Low Very Low Very Low
Osteoarthritis 12 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 72 97.32 Very High Very High Very High
Arthritis 12 89.52 High High
Leukemia 3 85.16 High High
INFLAMMATION 36 66.00 Quite High
Death 6 53.04 Quite High
Rheumatoid Arthritis 21 5.00 Very Low Very Low Very Low
Osteoarthritis 12 5.00 Very Low Very Low Very Low
Rheumatic Diseases 12 5.00 Very Low Very Low Very Low
Pathologic Processes 6 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To explore further the possible mechanism of the enhanced apoptotic cell clearance after GTH treatment, mRNA of GTH-treated RAW264.7 cells was analyzed for TG2 expression and a significantly increased TG2 mRNA expression was found in GTH-treated cells (Figure 5E).


Transcription (found) of TG2 in apoptotic cell associated with apoptosis
1) Confidence 0.28 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2988746 Disease Relevance 0.67 Pain Relevance 0.34
To explore further the possible mechanism of the enhanced apoptotic cell clearance after GTH treatment, mRNA of GTH-treated RAW264.7 cells was analyzed for TG2 expression and a significantly increased TG2 mRNA expression was found in GTH-treated cells (Figure 5E).


Transcription (expression) of TG2 in apoptotic cell associated with apoptosis
2) Confidence 0.28 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2988746 Disease Relevance 0.67 Pain Relevance 0.34
To assess the effects of GTH on the mRNA expression of TG2 of RAW264.7 cells by RT-PCR, RAW264.7 cells were incubated with GTH (165 ?
Transcription (expression) of TG2
3) Confidence 0.24 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2988746 Disease Relevance 0.20 Pain Relevance 0

General Comments

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