INT345151

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Context Info
Confidence 0.20
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.33
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Lpar2) cell adhesion (Trip6) cytoskeleton (Trip6)
nucleus (Trip6) signal transducer activity (Lpar2) cytoplasm (Trip6)
Trip6 (Mus musculus)
Lpar2 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 8 49.36 Quite Low
antagonist 30 24.64 Low Low
agonist 30 5.00 Very Low Very Low Very Low
fibrosis 18 5.00 Very Low Very Low Very Low
Neuropathic pain 16 5.00 Very Low Very Low Very Low
dorsal root ganglion 8 5.00 Very Low Very Low Very Low
Pain 8 5.00 Very Low Very Low Very Low
Potency 6 5.00 Very Low Very Low Very Low
alcohol 4 5.00 Very Low Very Low Very Low
Multiple sclerosis 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 30 99.36 Very High Very High Very High
Ovarian Cancer 32 74.48 Quite High
Cancer 48 65.36 Quite High
Aggression 4 33.80 Quite Low
Pressure And Volume Under Development 4 15.64 Low Low
Targeted Disruption 30 5.00 Very Low Very Low Very Low
Metastasis 20 5.00 Very Low Very Low Very Low
Neuropathic Pain 20 5.00 Very Low Very Low Very Low
Infection 14 5.00 Very Low Very Low Very Low
Disease 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
LPA2 can form a ternary complex with TRIP6 and NHERF2 in such a way that TRIP6 and NHERF2 also attach to each other.
TRIP6 Binding (complex) of LPA2
1) Confidence 0.20 Published 2010 Journal British Journal of Pharmacology Section Body Doc Link PMC2989581 Disease Relevance 0.68 Pain Relevance 0
TRIP6 also binds to the –CXXC motif in LPA2 via its LIM3 domain completing the ternary complex (Figure 6).
TRIP6 Binding (binds) of LPA2
2) Confidence 0.15 Published 2010 Journal British Journal of Pharmacology Section Body Doc Link PMC2989581 Disease Relevance 0.66 Pain Relevance 0

General Comments

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