INT345165

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.24
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Lpar5) nucleus (Dmbx1) DNA binding (Dmbx1)
signal transducer activity (Lpar5)
Lpar5 (Mus musculus)
Dmbx1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 15 99.74 Very High Very High Very High
antagonist 15 77.28 Quite High
fibrosis 9 5.00 Very Low Very Low Very Low
Neuropathic pain 8 5.00 Very Low Very Low Very Low
dorsal root ganglion 4 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 24 87.12 High High
Metastasis 10 81.52 Quite High
Breast Cancer 3 81.08 Quite High
Ovarian Cancer 16 72.24 Quite High
Skin Cancer 3 62.40 Quite High
Targeted Disruption 15 57.36 Quite High
Aggression 2 50.80 Quite High
Malignant Neoplastic Disease 2 44.08 Quite Low
Apoptosis 15 33.36 Quite Low
Disease 7 18.40 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Another new direction is to explore agonists of LPA4 and LPA5 that also inhibit ATX.
LPA5 Negative_regulation (inhibit) of ATX associated with agonist
1) Confidence 0.05 Published 2010 Journal British Journal of Pharmacology Section Body Doc Link PMC2989581 Disease Relevance 1.24 Pain Relevance 0.13

General Comments

This test has worked.

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