INT345176

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.11
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Lpar1, Car2) cytosol (Car2) extracellular space (Car2)
signal transduction (Lpar1) lyase activity (Car2) plasma membrane (Lpar1)
Lpar1 (Mus musculus)
Car2 (Mus musculus)
Pain Link Frequency Relevance Heat
Neuropathic pain 8 55.56 Quite High
antagonist 15 55.52 Quite High
Pain 4 51.12 Quite High
dorsal root ganglion 4 38.96 Quite Low
allodynia 2 29.40 Quite Low
chung model 1 24.80 Low Low
Action potential 2 18.32 Low Low
Dorsal horn 1 8.20 Low Low
agonist 15 5.00 Very Low Very Low Very Low
fibrosis 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 10 55.56 Quite High
Pain 4 51.12 Quite High
Nociception 2 47.48 Quite Low
Ganglion Cysts 5 38.96 Quite Low
Skin Cancer 3 27.84 Quite Low
Adenocarcinoma 1 25.36 Quite Low
Carcinoma 1 22.72 Low Low
Targeted Disruption 15 22.60 Low Low
Hypotrichosis 3 5.44 Low Low
Cancer 24 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
GPR87-G16-transfected CHO cells mobilize Ca2+ in response to LPA with an EC50 of 36 nM.
LPA Positive_regulation (response) of Gene_expression (mobilize) of Ca2
1) Confidence 0.03 Published 2010 Journal British Journal of Pharmacology Section Body Doc Link PMC2989581 Disease Relevance 0.11 Pain Relevance 0.16

General Comments

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