INT345181

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.42
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Trp53) mitochondrion (Trp53) endoplasmic reticulum (Trp53)
enzyme binding (Trp53) protein complex assembly (Trp53) DNA binding (Trp53)
Anatomy Link Frequency
urinary bladder 1
Gpr87 (Mus musculus)
Trp53 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 15 90.28 High High
Neuropathic pain 8 21.88 Low Low
Pain 4 17.44 Low Low
dorsal root ganglion 4 5.28 Low Low
agonist 15 5.00 Very Low Very Low Very Low
fibrosis 9 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Skin Cancer 3 98.40 Very High Very High Very High
Adenocarcinoma 1 97.16 Very High Very High Very High
Carcinoma 1 95.84 Very High Very High Very High
Hypotrichosis 3 74.40 Quite High
Disease 7 57.36 Quite High
Neuropathic Pain 10 21.88 Low Low
Syndrome 1 18.48 Low Low
Pain 4 17.44 Low Low
Nociception 2 13.80 Low Low
Ganglion Cysts 5 5.28 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
GPR87 is under the transcriptional regulation of p53; shows a very high expression level in squamous cell carcinomas, lung adenocarcinomas and transitional carcinomas of the urinary bladder and is involved in promoting cell survival and proliferation (Glatt et al., 2008; Gugger et al., 2008; Zhang et al., 2009b).
GPR87 Regulation (regulation) of p53 in urinary bladder associated with adenocarcinoma, carcinoma and skin cancer
1) Confidence 0.01 Published 2010 Journal British Journal of Pharmacology Section Body Doc Link PMC2989581 Disease Relevance 0.42 Pain Relevance 0.05

General Comments

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