INT345184

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.62
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Lpar1, Rock1) signal transduction (Lpar1) Golgi apparatus (Rock1)
cytoskeleton (Rock1) plasma membrane (Lpar1) cytoskeleton organization (Rock1)
Lpar1 (Mus musculus)
Rock1 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 15 5.00 Very Low Very Low Very Low
agonist 15 5.00 Very Low Very Low Very Low
fibrosis 9 5.00 Very Low Very Low Very Low
Neuropathic pain 8 5.00 Very Low Very Low Very Low
dorsal root ganglion 4 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 15 96.96 Very High Very High Very High
Exencephaly /

Neural Tube Defects

1 93.20 High High
Embryonic Lethality 4 91.08 High High
Cancer 24 80.76 Quite High
Skin Cancer 3 78.48 Quite High
Hypoxia 1 78.40 Quite High
Thrombosis 4 54.24 Quite High
Ovarian Cancer 16 43.04 Quite Low
Staphylococcus Infection 1 18.88 Low Low
Hyperplasia 2 18.08 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This latter defect is due to a lack of LPA-mediated constitutive activation of the Rho-ROCK and LIM kinase pathways.
LPA Positive_regulation (activation) of Rho-ROCK
1) Confidence 0.00 Published 2010 Journal British Journal of Pharmacology Section Body Doc Link PMC2989581 Disease Relevance 0.53 Pain Relevance 0

General Comments

This test has worked.

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