INT345189

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.23
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Lpar1) plasma membrane (Lpar1) nucleus (Dmbx1)
DNA binding (Dmbx1) cytoplasm (Lpar1) signal transducer activity (Lpar1)
Dmbx1 (Mus musculus)
Lpar1 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 15 5.00 Very Low Very Low Very Low
agonist 15 5.00 Very Low Very Low Very Low
fibrosis 9 5.00 Very Low Very Low Very Low
Neuropathic pain 8 5.00 Very Low Very Low Very Low
dorsal root ganglion 4 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Skin Cancer 3 86.48 High High
Cancer 24 81.76 Quite High
Embryonic Lethality 4 62.16 Quite High
Targeted Disruption 15 35.60 Quite Low
Exencephaly /

Neural Tube Defects

1 31.84 Quite Low
Hypoxia 1 17.04 Low Low
Ovarian Cancer 16 5.00 Very Low Very Low Very Low
Apoptosis 15 5.00 Very Low Very Low Very Low
Metastasis 10 5.00 Very Low Very Low Very Low
Neuropathic Pain 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In extracellular biological fluids, LPA production is linked to ATX, which is a lysophospholipase D that cleaves the headgroup from lysophospholipids to generate LPA.
ATX Positive_regulation (generate) of LPA
1) Confidence 0.06 Published 2010 Journal British Journal of Pharmacology Section Body Doc Link PMC2989581 Disease Relevance 0.23 Pain Relevance 0

General Comments

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