INT345194

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.87
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Lpar1, VEGFA) signal transducer activity (Lpar1) signal transduction (Lpar1)
extracellular space (VEGFA) extracellular region (VEGFA) growth (VEGFA)
Lpar1 (Mus musculus)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 4 96.44 Very High Very High Very High
agonist 15 22.20 Low Low
antagonist 15 5.00 Very Low Very Low Very Low
fibrosis 9 5.00 Very Low Very Low Very Low
Neuropathic pain 8 5.00 Very Low Very Low Very Low
dorsal root ganglion 4 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ovarian Cancer 16 90.24 High High
Aggression 2 89.52 High High
Pressure And Volume Under Development 2 71.36 Quite High
Cancer 24 69.16 Quite High
Apoptosis 15 62.48 Quite High
Metastasis 10 46.32 Quite Low
Malignant Neoplastic Disease 2 44.96 Quite Low
Targeted Disruption 15 38.16 Quite Low
Neuropathic Pain 10 5.00 Very Low Very Low Very Low
Infection 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
LPA increases VEGF production, and VEGF in turn up-regulates ATX production, which increases LPA levels (Ptaszynska et al., 2008) – a potential feed-forward loop.
LPA Positive_regulation (increases) of Gene_expression (production) of VEGF
1) Confidence 0.07 Published 2010 Journal British Journal of Pharmacology Section Body Doc Link PMC2989581 Disease Relevance 0.87 Pain Relevance 0.10

General Comments

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