INT345196

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.14
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (VEGFA) signal transduction (Lpar2) growth (VEGFA)
extracellular region (VEGFA) proteinaceous extracellular matrix (VEGFA) cytoplasm (VEGFA)
Lpar2 (Mus musculus)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 8 98.80 Very High Very High Very High
agonist 30 30.76 Quite Low
antagonist 30 5.00 Very Low Very Low Very Low
fibrosis 18 5.00 Very Low Very Low Very Low
Neuropathic pain 16 5.00 Very Low Very Low Very Low
dorsal root ganglion 8 5.00 Very Low Very Low Very Low
Pain 8 5.00 Very Low Very Low Very Low
Potency 6 5.00 Very Low Very Low Very Low
alcohol 4 5.00 Very Low Very Low Very Low
Multiple sclerosis 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ovarian Cancer 32 98.80 Very High Very High Very High
Aggression 4 98.08 Very High Very High Very High
Pressure And Volume Under Development 4 79.92 Quite High
Cancer 48 77.72 Quite High
Apoptosis 30 58.88 Quite High
Metastasis 20 54.88 Quite High
Malignant Neoplastic Disease 4 53.52 Quite High
Targeted Disruption 30 46.72 Quite Low
Breast Cancer 6 5.24 Low Low
Neuropathic Pain 20 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
First, LPA2 promotes the production of vascular endothelial growth factor (VEGF), urokinase (uPA) and matrix metalloproteinases (MMP) (Zebrowski et al., 1999; Hu et al., 2001; Huang et al., 2004; So et al., 2004; 2005;).
LPA2 Positive_regulation (promotes) of Gene_expression (production) of vascular endothelial growth factor associated with metalloproteinase
1) Confidence 0.08 Published 2010 Journal British Journal of Pharmacology Section Body Doc Link PMC2989581 Disease Relevance 1.07 Pain Relevance 0.10
First, LPA2 promotes the production of vascular endothelial growth factor (VEGF), urokinase (uPA) and matrix metalloproteinases (MMP) (Zebrowski et al., 1999; Hu et al., 2001; Huang et al., 2004; So et al., 2004; 2005;).
LPA2 Positive_regulation (promotes) of Gene_expression (production) of VEGF associated with metalloproteinase
2) Confidence 0.06 Published 2010 Journal British Journal of Pharmacology Section Body Doc Link PMC2989581 Disease Relevance 1.07 Pain Relevance 0.10

General Comments

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