INT345307

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Context Info
Confidence 0.00
First Reported 2011
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 2.50
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (MMP15) protein modification process (MMP15) signal transduction (CXCL12)
extracellular space (CXCL12) extracellular region (CXCL12) cell adhesion (CXCL12)
CXCL12 (Homo sapiens)
MMP15 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 3 100.00 Very High Very High Very High
metalloproteinase 46 50.00 Quite Low
Inflammation 15 5.00 Very Low Very Low Very Low
rheumatoid arthritis 7 5.00 Very Low Very Low Very Low
Multiple sclerosis 4 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Neuropathic pain 1 5.00 Very Low Very Low Very Low
Demyelination 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Glioma 2 99.84 Very High Very High Very High
Skin Cancer 5 95.16 Very High Very High Very High
Lung Cancer 1 93.36 High High
Pancreatic Cancer 1 89.96 High High
Breast Cancer 6 88.84 High High
Metastasis 9 86.76 High High
Cancer 38 85.76 High High
Death 2 84.00 Quite High
Apoptosis 1 83.28 Quite High
Colon Cancer 4 83.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Chemokine CXCL12 upregulates MMP-15 expression in glioma cells and serves as an effector of CXCR4 signaling in these cells by promoting cell invasion [46].
Chemokine CXCL12 Positive_regulation (upregulates) of Gene_expression (expression) of MMP-15 associated with chemokine and glioma
1) Confidence 0.00 Published 2011 Journal Biochemistry Research International Section Body Doc Link PMC2989751 Disease Relevance 2.50 Pain Relevance 0.05

General Comments

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