INT345323

Context Info Confidence 0.33 First Reported 2011 Last Reported 2011 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.12 Pain Relevance 0.49

cytoplasm (MMP14)

Anatomy Link Frequency cleavage 1 MMP14 (Homo sapiens)

Pain Link Frequency Relevance Heat metalloproteinase 46 95.76 cytokine 2 86.48 chemokine 3 86.04 Inflammation 15 5.00 rheumatoid arthritis 7 5.00 Multiple sclerosis 4 5.00 Pain 3 5.00 Potency 2 5.00 Neuropathic pain 1 5.00 Demyelination 1 5.00

Disease Link Frequency Relevance Heat Cancer 38 61.44 Malignant Neoplastic Disease 2 6.08 INFLAMMATION 15 5.00 Metastasis 9 5.00 Disease 9 5.00 Rheumatoid Arthritis 7 5.00 Breast Cancer 6 5.00 Demyelinating Disease 5 5.00 Skin Cancer 5 5.00 Carcinoma 4 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The hemopexin-like domain of MMP-14 and -16 are essential for the cleavage of fibrillar collagens.

Protein_catabolism (cleavage) of MMP-14 in cleavage

1) Confidence 0.33 Published 2011 Journal Biochemistry Research International Section Body Doc Link PMC2989751 Disease Relevance 0.12 Pain Relevance 0.49

General Comments

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