INT345368

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 6
Disease Relevance 7.25
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (Krt8) nucleus (Krt8) cytoplasm (Krt8)
Krt8 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 36 97.80 Very High Very High Very High
anesthesia 18 5.00 Very Low Very Low Very Low
isoflurane 18 5.00 Very Low Very Low Very Low
antagonist 12 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Metastasis 372 99.62 Very High Very High Very High
Cancer 690 99.48 Very High Very High Very High
Body Weight 18 87.60 High High
Carcinoma 72 86.56 High High
Adenocarcinoma 12 74.88 Quite High
Apoptosis 54 73.76 Quite High
Advanced Or Metastatic Breast Cancer 12 60.88 Quite High
Malignant Neoplastic Disease 18 57.12 Quite High
Breast Cancer 36 56.32 Quite High
Recurrence 6 51.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, pEndo significantly decreased in all organs with metastasis as compared to the control or pesVEGFR-2 groups.


Negative_regulation (decreased) of pEndo associated with metastasis
1) Confidence 0.00 Published 2010 Journal BMC Med Section Body Doc Link PMC2989928 Disease Relevance 1.10 Pain Relevance 0
Survival rates tended to be prolonged in the pesVEGFR-2 and pEndo groups, although this tendency was not statistically significant.
Negative_regulation (prolonged) of pEndo
2) Confidence 0.00 Published 2010 Journal BMC Med Section Body Doc Link PMC2989928 Disease Relevance 1.30 Pain Relevance 0
Tumor volume was significantly reduced in the pesVEGFR-2 and pEndo groups, and this reduction was associated with decreased cell proliferation as assessed by BrdU labeling indices.
Negative_regulation (reduced) of pEndo associated with cancer
3) Confidence 0.00 Published 2010 Journal BMC Med Section Body Doc Link PMC2989928 Disease Relevance 1.48 Pain Relevance 0
The average number of all organs with metastasis was significantly decreased in the pesVEGFR-2 and pEndo groups as compared to the pVec group.
Negative_regulation (decreased) of pEndo associated with metastasis
4) Confidence 0.00 Published 2010 Journal BMC Med Section Body Doc Link PMC2989928 Disease Relevance 1.22 Pain Relevance 0
Tumor volume increases were significantly suppressed in the pesVEGFR-2 and pEndo groups from Week 2 to the end of the study as compared to the pVec group.
Negative_regulation (suppressed) of pEndo associated with cancer
5) Confidence 0.00 Published 2010 Journal BMC Med Section Body Doc Link PMC2989928 Disease Relevance 0.99 Pain Relevance 0.14
As shown in Figure 1G, the levels were significantly decreased in the pesVEGFR-2 and pEndo groups as compared to the control group.
Negative_regulation (decreased) of pEndo
6) Confidence 0.00 Published 2010 Journal BMC Med Section Body Doc Link PMC2989928 Disease Relevance 1.15 Pain Relevance 0.18

General Comments

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