INT345374
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
In addition, VEGFR-3, the VEGF-C receptor, is predominantly expressed on lymphatic endothelial cells [29], and VEGF-C-dependent activation of VEGFR-3 stimulates the growth of lymphatic endothelial cells and lymphatics [30]. | |||||||||||||||
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The growth of blood vessels (angiogenesis) is primarily initiated by activation of VEGFR-1 and VEGFR-2 by VEGF-A, whereas lymphangiogenesis is predominantly driven by VEGF-C, which activates VEGFR-2 and VEGFR-3 expressed in lymphatic endothelial cells. | |||||||||||||||
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