INT345483

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Context Info
Confidence 0.16
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.63
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (MYC, PMAIP1) nucleoplasm (MYC) mitochondrion (PMAIP1)
DNA binding (MYC) protein complex (MYC) cytosol (PMAIP1)
MYC (Homo sapiens)
PMAIP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
peripheral neuropathy 13 5.00 Very Low Very Low Very Low
dexamethasone 10 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Duloxetine 1 5.00 Very Low Very Low Very Low
anticonvulsant 1 5.00 Very Low Very Low Very Low
Gabapentin 1 5.00 Very Low Very Low Very Low
vincristine 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Serotonin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 12 93.48 High High
Apoptosis 11 68.40 Quite High
Mantle-cell Lymphoma 1 62.52 Quite High
Skin Cancer 1 61.52 Quite High
Stress 1 36.40 Quite Low
Hypoxia 1 31.64 Quite Low
Death 1 16.68 Low Low
Neuropathic Pain 15 5.00 Very Low Very Low Very Low
Peripheral Neuropathy 13 5.00 Very Low Very Low Very Low
Multiple Myeloma 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The interaction of NOXA and c-myc also provides a possible rationale for the encouraging clinical data noted thus far when histone deacetylase (HDAC) inhibitors are combined with bortezomib.
c-myc Binding (interaction) of NOXA
1) Confidence 0.16 Published 2010 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2990320 Disease Relevance 0.63 Pain Relevance 0

General Comments

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