INT3459

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Context Info
Confidence 0.18
First Reported 1978
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.34
Pain Relevance 1.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Olfr145) plasma membrane (Olfr145) signal transducer activity (Olfr145)
Olfr145 (Mus musculus)
Pain Link Frequency Relevance Heat
Crohn's disease 4 100.00 Very High Very High Very High
Dopamine 7 99.70 Very High Very High Very High
Paracetamol 2 94.16 High High
spinal inflammation 7 92.96 High High
lidocaine 5 92.88 High High
adenocard 1 82.36 Quite High
Inflammation 2 75.00 Quite High
Catecholamine 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Disease 6 100.00 Very High Very High Very High
Low Back Pain 7 92.96 High High
Inflammatory Bowel Disease 4 89.44 High High
Celiac Disease 2 87.48 High High
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Norepinephrine and high-dose dopamine significantly increased k12, while low-dose dopamine significantly increased k21 and ke compared with control values.
Positive_regulation (increased) of k21 associated with dopamine
1) Confidence 0.18 Published 1998 Journal Life Sci. Section Abstract Doc Link 9651106 Disease Relevance 0 Pain Relevance 0.82
Significant changes were observed after 40% ethanol, an increase of AUC, beta, k12, k21, V2 and t1/2 alpha, decrease of Cmax and prolongation of tmax.
Positive_regulation (increase) of k21
2) Confidence 0.15 Published 1978 Journal Pol J Pharmacol Pharm Section Abstract Doc Link 755241 Disease Relevance 0 Pain Relevance 0.17
Furthermore, IgG antibody levels were significantly elevated in CD patients to K2, K17, K21, K26, K36 and K50; IgA to K2, K3, K21, K26, K36 and K50; and IgM to K2, K3, K17, K21 and K50.
Positive_regulation (elevated) of K21 associated with crohn's disease
3) Confidence 0.04 Published 1998 Journal Br. J. Rheumatol. Section Abstract Doc Link 9651080 Disease Relevance 1.34 Pain Relevance 0.76

General Comments

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