INT345946

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.56
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (CYP3A4) oxidoreductase activity (CYP3A4) endoplasmic reticulum (CYP3A4)
enzyme binding (CYP3A4) lipid metabolic process (CYP3A4) cytoplasm (CYP3A4)
CYP3A4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Calcium channel 2 99.98 Very High Very High Very High
Versed 2 58.40 Quite High
Bioavailability 8 47.32 Quite Low
headache 2 20.76 Low Low
Central nervous system 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Leukopenia 2 96.20 Very High Very High Very High
Uveitis 2 95.60 Very High Very High Very High
Fungal Infection 34 90.88 High High
Headache 2 20.76 Low Low
Appetite Loss 2 18.16 Low Low
Arrhythmia Under Development 2 17.36 Low Low
Endemic Invasive Fungal Infection 46 5.00 Very Low Very Low Very Low
Aspergillus Infection 26 5.00 Very Low Very Low Very Low
Infection 24 5.00 Very Low Very Low Very Low
Disease 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Posaconazole may also increase concentrations of vinca alkaloids, digoxin, HMG-CoA reductase inhibitors metabolized by CYP3A4, and calcium channel blockers metabolized by CYP3A4.7
Negative_regulation (inhibitors) of Localization (metabolized) of CYP3A4 associated with calcium channel
1) Confidence 0.09 Published 2010 Journal Drug Design, Development and Therapy Section Body Doc Link PMC2990390 Disease Relevance 0.28 Pain Relevance 0.08
Posaconazole may also increase concentrations of vinca alkaloids, digoxin, HMG-CoA reductase inhibitors metabolized by CYP3A4, and calcium channel blockers metabolized by CYP3A4.7
Negative_regulation (blockers) of Localization (metabolized) of CYP3A4 associated with calcium channel
2) Confidence 0.09 Published 2010 Journal Drug Design, Development and Therapy Section Body Doc Link PMC2990390 Disease Relevance 0.28 Pain Relevance 0.08

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox