INT345950

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Context Info
Confidence 0.12
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 3.63
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Arid1a) intracellular (Arid1a) DNA binding (Arid1a)
Arid1a (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 3 90.84 High High
anesthesia 21 90.72 High High
imagery 3 63.28 Quite High
Inflammation 36 59.96 Quite High
cva 6 34.08 Quite Low
Regional anesthesia 3 5.00 Very Low Very Low Very Low
corticosteroid 3 5.00 Very Low Very Low Very Low
epidural 3 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
backache 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity-hypoventilation Syndrome 84 100.00 Very High Very High Very High
Hypercapnia 30 100.00 Very High Very High Very High
Obesity 501 99.68 Very High Very High Very High
Weight Loss 21 95.66 Very High Very High Very High
Disease 18 88.88 High High
Weight Gain 18 75.16 Quite High
Morbid Obesity 9 74.20 Quite High
Respiratory Failure 9 74.00 Quite High
Pulmonary Disease 75 72.16 Quite High
Insulin Resistance 9 68.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, two patients were found to have an increase in their AHI despite significant weight loss.26 A meta-analysis by Greenburg et al39 representing 342 patients in the year 2009, showed similar results with bariatric surgery significantly reducing AHI, however, to a mean value still consistent with moderately severe OSA.39
Positive_regulation (severe) of Gene_expression (severe) of OSA associated with weight loss
1) Confidence 0.12 Published 2010 Journal Int J Gen Med Section Body Doc Link PMC2990395 Disease Relevance 1.01 Pain Relevance 0
In particular, OSA and OHS should always be considered in the obese patient undergoing assessment for surgery.27
Positive_regulation (considered) of Gene_expression (considered) of OSA associated with obesity and obesity-hypoventilation syndrome
2) Confidence 0.12 Published 2010 Journal Int J Gen Med Section Body Doc Link PMC2990395 Disease Relevance 1.10 Pain Relevance 0.32
Furthermore, in OSA with chronic hypercapnia, the leptin levels were even higher.44 Finally, Chin et al45 demonstrated a noticeable reduction in leptin levels following CPAP treatment.45 All these studies propose an important role of leptin and highlight the potential significance of the development of leptin resistance in obesity and OHS.
Positive_regulation (following) of Gene_expression (were) of OSA associated with obesity, hypercapnia and obesity-hypoventilation syndrome
3) Confidence 0.12 Published 2010 Journal Int J Gen Med Section Body Doc Link PMC2990395 Disease Relevance 1.52 Pain Relevance 0.05

General Comments

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