INT345951

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Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 6.11
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Arid1a) intracellular (Arid1a) DNA binding (Arid1a)
Anatomy Link Frequency
neck 1
nasal 1
respiratory 1
Arid1a (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 60 98.48 Very High Very High Very High
alcohol 5 68.88 Quite High
anesthesia 35 59.76 Quite High
epidural 5 59.32 Quite High
Regional anesthesia 5 58.36 Quite High
cva 10 5.00 Very Low Very Low Very Low
corticosteroid 5 5.00 Very Low Very Low Very Low
backache 5 5.00 Very Low Very Low Very Low
Inflammatory mediators 5 5.00 Very Low Very Low Very Low
tolerance 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity-hypoventilation Syndrome 140 99.92 Very High Very High Very High
Pulmonary Disease 125 99.60 Very High Very High Very High
Obesity 835 99.50 Very High Very High Very High
INFLAMMATION 65 98.48 Very High Very High Very High
Atelectasis 45 97.84 Very High Very High Very High
Weight Loss 35 92.40 High High
Sleep Disorders 20 90.92 High High
Metabolic Syndrome 15 89.12 High High
Morbid Obesity 15 87.92 High High
Necrosis 5 86.88 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the study, OSA severity reduced by 50%.
Negative_regulation (reduced) of OSA
1) Confidence 0.10 Published 2010 Journal Int J Gen Med Section Body Doc Link PMC2990395 Disease Relevance 0.46 Pain Relevance 0
With an “obesity epidemic” currently underway, the incidence and prevalence of OSA have now reached new heights and is predicted to rise even further.25

Pathophysiology of OSA

Negative_regulation (predicted) of OSA associated with obesity
2) Confidence 0.10 Published 2010 Journal Int J Gen Med Section Body Doc Link PMC2990395 Disease Relevance 1.51 Pain Relevance 0
Even more interestingly, abdominal circumference has proven to be a better predictor of OSA than both neck circumference and BMI.27–29
Negative_regulation (predictor) of OSA in neck associated with obesity
3) Confidence 0.10 Published 2010 Journal Int J Gen Med Section Body Doc Link PMC2990395 Disease Relevance 1.02 Pain Relevance 0
This is especially true in OSA or OHS patients.67 Joris et al67 examined the effect of nasal BiPAP in obese patients given for the first 24 hours after undergoing gastroplasty.
Negative_regulation (true) of OSA in nasal associated with obesity and obesity-hypoventilation syndrome
4) Confidence 0.10 Published 2010 Journal Int J Gen Med Section Body Doc Link PMC2990395 Disease Relevance 1.00 Pain Relevance 0.20
Adipose tissue is now regarded as an endocrine organ, with release of adipocytokines affecting systemic inflammation possibly triggered by hypoxemia induced by obesity and related respiratory disorders like OSA, OHS, or COPD.13,18
Negative_regulation (disorders) of OSA in respiratory associated with pulmonary disease, inflammation, obesity and obesity-hypoventilation syndrome
5) Confidence 0.10 Published 2010 Journal Int J Gen Med Section Body Doc Link PMC2990395 Disease Relevance 2.06 Pain Relevance 0.12

General Comments

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