INT345961

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 3.73
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
fat 1
skeletal muscle 1
D0Ffm3 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 24 70.04 Quite High
alcohol 2 20.48 Low Low
anesthesia 14 15.68 Low Low
cva 4 5.00 Very Low Very Low Very Low
Regional anesthesia 2 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
epidural 2 5.00 Very Low Very Low Very Low
backache 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Disease 50 98.72 Very High Very High Very High
Respiratory Disease 8 98.32 Very High Very High Very High
Overweight 16 97.12 Very High Very High Very High
Obesity 334 95.92 Very High Very High Very High
Dyspnea 34 94.24 High High
Weight Loss 14 82.24 Quite High
Pulmonary Heart Disease 4 76.84 Quite High
Pulmonary Hypertension 6 76.08 Quite High
Respiratory Failure 6 75.12 Quite High
Syndrome 4 72.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The use of oral steroid medication also increases; patients put on more weight and FM and undergo skeletal muscle deconditioning with loss of FFM.18
Negative_regulation (loss) of FFM in skeletal muscle
1) Confidence 0.03 Published 2010 Journal Int J Gen Med Section Body Doc Link PMC2990395 Disease Relevance 2.29 Pain Relevance 0.07
This may also be related to a reduction in the overall fat free mass (FFM – ie, muscle mass).18,22 This deficiency may contribute to the additional oxygen demand required for ventilation and may heighten sensation of breathlessness in obese patients.
Negative_regulation (reduction) of FFM in fat associated with obesity and dyspnea
2) Confidence 0.03 Published 2010 Journal Int J Gen Med Section Body Doc Link PMC2990395 Disease Relevance 1.44 Pain Relevance 0

General Comments

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