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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.35
Pain Relevance 2.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (SLC1A1) transmembrane transport (SLC1A1)
Anatomy Link Frequency
synaptic clefts 2
SLC1A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Glutamate 5 100.00 Very High Very High Very High
dexamethasone 12 99.98 Very High Very High Very High
Central nervous system 1 99.28 Very High Very High Very High
Morphine 8 98.62 Very High Very High Very High
analgesia 11 95.92 Very High Very High Very High
Perioperative pain 5 90.68 High High
Analgesic 37 90.08 High High
tolerance 4 89.28 High High
Opioid 19 87.12 High High
intrathecal 6 77.12 Quite High
Disease Link Frequency Relevance Heat
Post Operative Pain 5 90.68 High High
Pain 132 69.68 Quite High
Cancer Pain 3 64.80 Quite High
Vomiting 1 49.12 Quite Low
Syndrome 5 33.36 Quite Low
Nociception 6 17.76 Low Low
Herpes Zoster 1 16.56 Low Low
Neuropathic Pain 15 15.28 Low Low
Functional Bowel Disorder 2 13.44 Low Low
Sleep Disorders 3 12.28 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Morphine increases central nervous system glutamate levels and dexamethasone increases glutamate transporter expression, which increases glutamate clearance from synaptic clefts [26-28].
Positive_regulation (increases) of Gene_expression (expression) of glutamate transporter in synaptic clefts associated with glutamate, central nervous system, dexamethasone and morphine
1) Confidence 0.01 Published 2010 Journal F1000 Med Rep Section Body Doc Link PMC2990447 Disease Relevance 0.35 Pain Relevance 2.20

General Comments

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