INT34604

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Context Info
Confidence 0.31
First Reported 1984
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 11
Total Number 11
Disease Relevance 4.15
Pain Relevance 3.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ada) extracellular space (Ada) aging (Ada)
cell adhesion (Ada) plasma membrane (Ada) lysosome (Ada)
Anatomy Link Frequency
outflow 1
cerebrospinal fluid 1
spinal cord 1
neurons 1
Ada (Rattus norvegicus)
Pain Link Frequency Relevance Heat
adenocard 87 100.00 Very High Very High Very High
Spinal cord 6 99.90 Very High Very High Very High
agonist 104 99.38 Very High Very High Very High
Pain 4 99.30 Very High Very High Very High
Clonidine 3 98.94 Very High Very High Very High
anesthesia 21 97.32 Very High Very High Very High
antagonist 19 95.88 Very High Very High Very High
headache 2 87.88 High High
Enkephalin 3 66.48 Quite High
Catecholamine 1 55.60 Quite High
Disease Link Frequency Relevance Heat
Anxiety Disorder 156 100.00 Very High Very High Very High
Severe Combined Immunodeficiency 3 99.98 Very High Very High Very High
Meningoencephalitis 4 99.96 Very High Very High Very High
Pain 2 99.30 Very High Very High Very High
Agammaglobulinemia 1 99.22 Very High Very High Very High
Lymphatic System Cancer 2 98.34 Very High Very High Very High
Diabetes Mellitus 48 93.92 High High
Obesity 7 93.68 High High
Sleep Disorders 6 91.12 High High
Diabetes Complications 4 90.08 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Based on their size, shape and dendritic features, 4 morphologically distinct types of ADA-IR neurons were recognized in these septal structures.
ADA Binding (recognized) of in neurons
1) Confidence 0.31 Published 1988 Journal Brain Res. Section Abstract Doc Link 3046711 Disease Relevance 0 Pain Relevance 0.20
Adenosine, a modulator of pain processing in the spinal cord, is metabolized by adenosine kinase and adenosine deaminase.
adenosine deaminase Binding (metabolized) of in spinal cord associated with pain, adenocard and spinal cord
2) Confidence 0.28 Published 1995 Journal Brain Res. Section Abstract Doc Link 8616636 Disease Relevance 0.10 Pain Relevance 0.73
A case of hypogammaglobulinemia with enteroviral meningoencephalitis, associated with increased adenosine deaminase in cerebrospinal fluid.
adenosine deaminase Binding (associated) of in cerebrospinal fluid associated with adenocard, meningoencephalitis and agammaglobulinemia
3) Confidence 0.22 Published 2009 Journal Iran J Allergy Asthma Immunol Section Title Doc Link 19671942 Disease Relevance 0.79 Pain Relevance 0.23
We posited that the AA subscale would be strongly associated with the anticipatory dental anxiety (ADA) items of the MDAS as individuals who tend to be 'physiological reactors' [42] will score highly on items that indicate imminent future exposure to the dental situation.
ADA Binding (associated) of associated with anxiety disorder
4) Confidence 0.19 Published 2008 Journal Health Qual Life Outcomes Section Body Doc Link PMC2289811 Disease Relevance 1.18 Pain Relevance 0
Cerebral lymphoma in an adenosine deaminase-deficient patient with severe combined immunodeficiency receiving polyethylene glycol-conjugated adenosine deaminase.
polyethylene glycol-conjugated adenosine deaminase Binding (receiving) of associated with adenocard, lymphatic system cancer and severe combined immunodeficiency
5) Confidence 0.19 Published 2005 Journal Pediatrics Section Title Doc Link 16263974 Disease Relevance 0.80 Pain Relevance 0.22
This is related to the traditional linkage of accreditation of postdoctoral training programs to ADA specialty recognition.
ADA Binding (recognition) of
6) Confidence 0.15 Published 2002 Journal Tex Dent J Section Abstract Doc Link 11922015 Disease Relevance 0.09 Pain Relevance 0.25
To address this issue and those of other non-ADA-recognized disciplines, the CDA is currently in the initial stages of developing requirements for accrediting non-ADA recognized postdoctoral training programs.
ADA Binding (recognized) of
7) Confidence 0.15 Published 2002 Journal Tex Dent J Section Abstract Doc Link 11922015 Disease Relevance 0.08 Pain Relevance 0.28
However, the ADA House declined to recognize dental anesthesiology as a dental specialty on three separate occasions even though the ADA Council on Dental Education felt all requirements were met and favorably recommended specialty recognition in all three instances.
ADA Binding (recognize) of
8) Confidence 0.15 Published 2002 Journal Tex Dent J Section Abstract Doc Link 11922015 Disease Relevance 0.14 Pain Relevance 0.51
Upon agonist exposure (100 nM R-PIA, 2 h), ADA and A1R formed complexes on the cell surface, clustered and internalized together to intracellular compartments.
ADA Binding (internalized) of associated with agonist
9) Confidence 0.12 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2245999 Disease Relevance 0 Pain Relevance 0.29
Both the ADA 2009 and the SIGN guidelines recommend undertaking a complete preconception evaluation of the women's medical and obstetric history.


ADA Binding (recommend) of
10) Confidence 0.03 Published 2010 Journal BMC Womens Health Section Body Doc Link PMC2834595 Disease Relevance 0.80 Pain Relevance 0
Moreover, clonidine inhibited the FFA outflow initiated by theophylline associated with adenosine deaminase.
adenosine deaminase Binding (associated) of in outflow associated with adenocard and clonidine
11) Confidence 0.03 Published 1984 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 6086878 Disease Relevance 0.17 Pain Relevance 0.40

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