INT34605

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Context Info
Confidence 0.80
First Reported 1988
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 0.13
Pain Relevance 1.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ada) extracellular space (Ada) aging (Ada)
cell adhesion (Ada) plasma membrane (Ada) lysosome (Ada)
Anatomy Link Frequency
habenula 3
blood 2
saliva 1
Ada (Rattus norvegicus)
Pain Link Frequency Relevance Heat
adenocard 33 100.00 Very High Very High Very High
Enkephalin 9 99.68 Very High Very High Very High
Serotonin 3 97.00 Very High Very High Very High
antagonist 1 80.44 Quite High
Pain 3 77.12 Quite High
Inflammation 3 64.72 Quite High
cytokine 3 63.68 Quite High
tetrodotoxin 1 55.36 Quite High
Action potential 1 54.64 Quite High
substance P 3 25.00 Low Low
Disease Link Frequency Relevance Heat
Pain 3 77.12 Quite High
INFLAMMATION 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Adenosine deaminase (ADA) was localized within several types of neurons within the septum and in septal efferent projections to the habenula by immunohistochemical, biochemical, retrograde tracing and lesion methods.
Localization (localized) of Adenosine deaminase in habenula associated with adenocard
1) Confidence 0.80 Published 1988 Journal Brain Res. Section Abstract Doc Link 3046711 Disease Relevance 0 Pain Relevance 0.09
Adenosine deaminase (ADA) was localized within several types of neurons within the septum and in septal efferent projections to the habenula by immunohistochemical, biochemical, retrograde tracing and lesion methods.
Localization (localized) of ADA in habenula associated with adenocard
2) Confidence 0.80 Published 1988 Journal Brain Res. Section Abstract Doc Link 3046711 Disease Relevance 0 Pain Relevance 0.09
Comparisons of the habenular localization of ADA-IR and enkephalin-IR elements showed that fibers labelled for either ADA or enkephalin occupied distinct, non-overlapping regions within the dorsal half of the medial habenula.
Localization (localization) of ADA in habenula associated with enkephalin
3) Confidence 0.80 Published 1988 Journal Brain Res. Section Abstract Doc Link 3046711 Disease Relevance 0 Pain Relevance 0.27
Our findings are in keeping with the hypothesis that ADA secretion, along with a less-efficient dipyridamole-sensitive nucleoside transport system, may restrict endogenous adenosine actions to the synaptic region channelling to facilitatory A2A receptors activation.
Localization (secretion) of ADA associated with adenocard
4) Confidence 0.78 Published 2006 Journal Auton Neurosci Section Abstract Doc Link 16563876 Disease Relevance 0 Pain Relevance 0.51
Evidence for secretion of ADA during blood feeding by Aedes aegypti includes the presence of ADA activity in warm solutions probed through a membrane by mosquitoes and in serotonin-induced saliva and a statistically significant reduction in the levels of the enzyme in Aedes aegypti following a blood meal.
Localization (secretion) of ADA in blood associated with serotonin
5) Confidence 0.71 Published 2001 Journal J. Exp. Biol. Section Abstract Doc Link 11441041 Disease Relevance 0.05 Pain Relevance 0.21
Evidence for secretion of ADA during blood feeding by Aedes aegypti includes the presence of ADA activity in warm solutions probed through a membrane by mosquitoes and in serotonin-induced saliva and a statistically significant reduction in the levels of the enzyme in Aedes aegypti following a blood meal.
Localization (secretion) of ADA in blood associated with serotonin
6) Confidence 0.66 Published 2001 Journal J. Exp. Biol. Section Abstract Doc Link 11441041 Disease Relevance 0 Pain Relevance 0.15
We could not demonstrate, however, that C. quinquefasciatus secrete ADA in their saliva.
Localization (secrete) of ADA in saliva
7) Confidence 0.58 Published 2001 Journal J. Exp. Biol. Section Abstract Doc Link 11441041 Disease Relevance 0.08 Pain Relevance 0.30

General Comments

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