INT346130

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il17a, TNFSF11) extracellular region (Il17a, TNFSF11) cell differentiation (TNFSF11)
plasma membrane (TNFSF11) intracellular (TNFSF11) response to stress (TNFSF11)
Il17a (Mus musculus)
TNFSF11 (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 8 98.80 Very High Very High Very High
Inflammation 10 98.48 Very High Very High Very High
cytokine 19 97.96 Very High Very High Very High
rheumatoid arthritis 98 84.72 Quite High
spinal inflammation 1 10.48 Low Low
methotrexate 9 5.00 Very Low Very Low Very Low
psoriasis 3 5.00 Very Low Very Low Very Low
Crohn's disease 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 7 98.80 Very High Very High Very High
INFLAMMATION 9 98.48 Very High Very High Very High
Rheumatoid Arthritis 98 84.72 Quite High
Disease 18 63.84 Quite High
Necrosis 3 50.00 Quite Low
Cancer 3 50.00 Quite Low
Low Back Pain 1 10.48 Low Low
Multiple Sclerosis 5 5.00 Very Low Very Low Very Low
Psoriasis 3 5.00 Very Low Very Low Very Low
Autoimmune Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mechanistically, IL-17 promotes osteoclastogenesis, partly through upregulation of RANKL expression [35], and also synergises with other inflammatory cytokines, such as TNF?
IL-17 Positive_regulation (upregulation) of Gene_expression (expression) of RANKL associated with inflammation and cytokine
1) Confidence 0.08 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2991017 Disease Relevance 0.61 Pain Relevance 0.41

General Comments

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