INT346218

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.71
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Mdk) signal transduction (Kras) mitochondrion (Kras)
extracellular region (Mdk) plasma membrane (Kras) GTPase activity (Kras)
Kras (Mus musculus)
Mdk (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 74 79.36 Quite High
Inflammation 7 72.80 Quite High
cytokine 5 71.76 Quite High
Arthritis 10 51.44 Quite High
spinal inflammation 10 31.24 Quite Low
psoriasis 2 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 74 79.36 Quite High
INFLAMMATION 5 72.80 Quite High
Arthritis 12 51.44 Quite High
Low Back Pain 10 31.24 Quite Low
Sarcoma 3 5.00 Very Low Very Low Very Low
Psoriasis 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low
Arthropathy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Following RAS activation, BRAF is recruited to the cell membrane and then phosphorylates MEK in the cytoplasm.
Positive_regulation (activation) of RAS Positive_regulation (Following) of Phosphorylation (phosphorylates) of MEK
1) Confidence 0.01 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2991030 Disease Relevance 0.71 Pain Relevance 0.42

General Comments

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