INT346221

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Context Info
Confidence 0.11
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.67
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

kinase activity (Braf, Map2k2) cytosol (Map2k2) signal transduction (Braf)
plasma membrane (Braf) nucleus (Braf) cytoplasm (Braf)
Braf (Mus musculus)
Map2k2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 7 99.08 Very High Very High Very High
cytokine 5 97.88 Very High Very High Very High
rheumatoid arthritis 74 91.52 High High
Kinase C 1 84.40 Quite High
spinal inflammation 10 5.00 Very Low Very Low Very Low
Arthritis 10 5.00 Very Low Very Low Very Low
psoriasis 2 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 12 99.08 Very High Very High Very High
Rheumatoid Arthritis 74 91.52 High High
Sarcoma 3 73.48 Quite High
Arthropathy 1 44.56 Quite Low
INFLAMMATION 5 44.00 Quite Low
Low Back Pain 10 5.00 Very Low Very Low Very Low
Psoriasis 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation of BRAF leads to activation of MEK1 and/or MEK2.
Positive_regulation (Activation) of BRAF Positive_regulation (leads) of Positive_regulation (activation) of MEK2
1) Confidence 0.11 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2991030 Disease Relevance 0.67 Pain Relevance 0.39

General Comments

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