INT346224

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Context Info
Confidence 0.14
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.62
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Braf, Map2k1) nucleus (Braf, Map2k1) plasma membrane (Braf, Map2k1)
kinase activity (Braf, Map2k1) Golgi apparatus (Map2k1) cell proliferation (Map2k1)
Braf (Mus musculus)
Map2k1 (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 74 97.44 Very High Very High Very High
Arthritis 10 32.52 Quite Low
spinal inflammation 10 31.68 Quite Low
Inflammation 7 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
psoriasis 2 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 74 97.44 Very High Very High Very High
Disease 2 94.96 High High
Arthritis 12 32.52 Quite Low
Low Back Pain 10 31.68 Quite Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Sarcoma 3 5.00 Very Low Very Low Very Low
Psoriasis 2 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low
Arthropathy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
No difference was observed in the recognition of BRAF peptides between autoantibodies to BRAF that inhibited or activated MEK1 phosphorylation (data not shown).


BRAF Negative_regulation (inhibited) of Phosphorylation (phosphorylation) of MEK1
1) Confidence 0.14 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2991030 Disease Relevance 0.62 Pain Relevance 0.22

General Comments

This test has worked.

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