INT346228

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Context Info
Confidence 0.44
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.68
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (MAP2K6, MAPK14) nucleoplasm (MAP2K6, MAPK14) signal transduction (MAP2K6, MAPK14)
nucleus (MAP2K6, MAPK14) response to stress (MAP2K6, MAPK14) cytoplasm (MAP2K6, MAPK14)
Anatomy Link Frequency
fibroblasts 2
MAP2K6 (Homo sapiens)
MAPK14 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 8 99.00 Very High Very High Very High
Osteoarthritis 103 88.32 High High
Inflammation 16 17.08 Low Low
Arthritis 8 6.36 Low Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
rheumatoid arthritis 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 1 100.00 Very High Very High Very High
Osteoarthritis 104 88.32 High High
INFLAMMATION 14 17.08 Low Low
Arthritis 9 6.36 Low Low
Disease 5 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 4 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Hypertrophy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For instance, MKK6 is the major activator of p38-MAPK in cells exposed to osmotic stress [13] and MKK3 is required for full activation of p38-MAPK in murine embryonic fibroblasts [38].
MKK6 Positive_regulation (activator) of Positive_regulation (activation) of p38 in fibroblasts associated with stress
1) Confidence 0.44 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2991031 Disease Relevance 0.68 Pain Relevance 0.34

General Comments

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