INT346230

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Context Info
Confidence 0.17
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.38
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IL1B) signal transduction (IL1B) extracellular space (IL1B)
aging (IL1B) extracellular region (IL1B) nucleolus (RUNX2)
Anatomy Link Frequency
chondrocytes 2
IL1B (Homo sapiens)
RUNX2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 103 100.00 Very High Very High Very High
Inflammation 16 5.00 Very Low Very Low Very Low
cytokine 8 5.00 Very Low Very Low Very Low
Arthritis 8 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
rheumatoid arthritis 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 104 100.00 Very High Very High Very High
INFLAMMATION 14 5.00 Very Low Very Low Very Low
Arthritis 9 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 4 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Hypertrophy 1 5.00 Very Low Very Low Very Low
Frailty 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation and DNA binding activity of RUNX-2 in human OA chondrocytes pretreated with PE (2 h) and then stimulated with IL-1?
IL-1 Positive_regulation (stimulated) of RUNX-2 Binding (binding) of in chondrocytes associated with osteoarthritis
1) Confidence 0.17 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2991031 Disease Relevance 0.38 Pain Relevance 0.19

General Comments

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