INT346259

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.58
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (TFAM) nucleus (TFAM) DNA binding (TFAM)
Anatomy Link Frequency
joint 2
TFAM (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 8 97.88 Very High Very High Very High
Inflammation 16 74.40 Quite High
cytokine 8 73.44 Quite High
Pain 2 73.04 Quite High
Osteoarthritis 103 57.44 Quite High
metalloproteinase 6 48.32 Quite Low
rheumatoid arthritis 4 43.44 Quite Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 9 97.88 Very High Very High Very High
Targeted Disruption 3 75.44 Quite High
INFLAMMATION 14 74.40 Quite High
Pain 1 73.04 Quite High
Disease 5 70.80 Quite High
Osteoarthritis 104 57.44 Quite High
Experimental Arthritis 1 55.20 Quite High
Rheumatoid Arthritis 4 43.44 Quite Low
Apoptosis 1 23.32 Low Low
Hypertrophy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These and other studies [17] clearly show that inhibition of specific MAPKs or transcription factor may be an effective approach for the inhibition of joint destruction in arthritis.
Regulation (effective) of Negative_regulation (inhibition) of transcription factor in joint associated with arthritis
1) Confidence 0.06 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2991031 Disease Relevance 0.58 Pain Relevance 0.29

General Comments

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