INT346261

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Context Info
Confidence 0.40
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.66
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (MKKS) protein folding (MKKS) cytosol (MKKS)
cytoskeleton (MKKS) intracellular (MKKS) cytoplasm (MKKS)
Anatomy Link Frequency
fibroblast 1
MKKS (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 103 99.20 Very High Very High Very High
cytokine 8 85.12 High High
Inflammation 16 29.72 Quite Low
Arthritis 8 19.00 Low Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
rheumatoid arthritis 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 104 99.20 Very High Very High Very High
Stress 1 77.04 Quite High
INFLAMMATION 14 29.72 Quite Low
Arthritis 9 19.00 Low Low
Disease 5 12.28 Low Low
Rheumatoid Arthritis 4 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Hypertrophy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both MKKs 3 and 6 are known to be phosphorylated in inflamed synovium and are constitutively expressed in fibroblast like synoviocytes (FLS) [37].
Gene_expression (expressed) of MKKs in fibroblast
1) Confidence 0.40 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2991031 Disease Relevance 0.66 Pain Relevance 0.34

General Comments

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