INT346369

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.37
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Tesc) nucleus (Tesc) cytoplasm (Tesc)
Anatomy Link Frequency
neurons 1
Tesc (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 138 96.64 Very High Very High Very High
Neurotransmitter 12 42.96 Quite Low
tetrodotoxin 42 5.00 Very Low Very Low Very Low
Central nervous system 18 5.00 Very Low Very Low Very Low
Action potential 15 5.00 Very Low Very Low Very Low
antagonist 9 5.00 Very Low Very Low Very Low
sodium channel 3 5.00 Very Low Very Low Very Low
nMDA receptor antagonist 3 5.00 Very Low Very Low Very Low
gABA 3 5.00 Very Low Very Low Very Low
Glutamate 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anaerobic Bacterial Infections 66 100.00 Very High Very High Very High
Injury 6 99.44 Very High Very High Very High
Disease 18 96.20 Very High Very High Very High
Autolysis 3 82.40 Quite High
Myocardial Infarction 3 74.32 Quite High
Paralysis 21 49.04 Quite Low
Targeted Disruption 18 5.00 Very Low Very Low Very Low
Infection 12 5.00 Very Low Very Low Very Low
Poisoning 6 5.00 Very Low Very Low Very Low
Toxicity 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TeNT is synthesized by Clostridium tetani, and is one of the most toxic substances known to humans; it causes the disease tetanus [2], [3].
Gene_expression (synthesized) of TeNT associated with anaerobic bacterial infections and disease
1) Confidence 0.03 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2991259 Disease Relevance 0.66 Pain Relevance 0.05
The Clostridium genus of bacteria are responsible for the production of the clostridial neurotoxins (CNTs), which include both tetanus neurotoxin (TeNT) and seven botulinum neurotoxins (BoNT/A–G) [1].
Gene_expression (production) of TeNT associated with anaerobic bacterial infections
2) Confidence 0.03 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2991259 Disease Relevance 0.62 Pain Relevance 0.05
TeNT is typically introduced through deep wounds, so it utilizes the MN as a mechanism of transport back to the spinal cord, where its enzymatic activity is focused on inhibitory neurons.
Gene_expression (introduced) of TeNT in neurons associated with injury and spinal cord
3) Confidence 0.03 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2991259 Disease Relevance 0.10 Pain Relevance 0.08

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox