INT346394

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Context Info
Confidence 0.36
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.16
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Sv2a) transmembrane transporter activity (Sv2a) endoplasmic reticulum (Sv2a)
transmembrane transport (Sv2a) cytoplasm (Sv2a)
Sv2a (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 46 81.44 Quite High
Action potential 5 11.36 Low Low
tetrodotoxin 14 5.00 Very Low Very Low Very Low
Central nervous system 6 5.00 Very Low Very Low Very Low
Neurotransmitter 4 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
sodium channel 1 5.00 Very Low Very Low Very Low
nMDA receptor antagonist 1 5.00 Very Low Very Low Very Low
gABA 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 6 93.08 High High
Poisoning 2 63.24 Quite High
Anaerobic Bacterial Infections 22 50.00 Quite Low
Infection 4 11.12 Low Low
Paralysis 7 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Autolysis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data indicate that loss of SV2 does not affect normal uptake of toxins that target SVs and furthermore, in contrast to previous suggestions, SV2A/B is not required for normal uptake of BoNT/F [50], [58].


Neg (not) Regulation (affect) of Negative_regulation (loss) of SV2
1) Confidence 0.36 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2991259 Disease Relevance 0.16 Pain Relevance 0.08

General Comments

This test has worked.

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