INT346395

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Context Info
Confidence 0.16
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.13
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

vesicle-mediated transport (Vamp2) plasma membrane (Vamp2) protein complex assembly (Vamp2)
Anatomy Link Frequency
neurons 2
Vamp2 (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 46 98.52 Very High Very High Very High
Action potential 5 16.60 Low Low
Central nervous system 6 15.68 Low Low
tetrodotoxin 14 5.00 Very Low Very Low Very Low
Neurotransmitter 4 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
sodium channel 1 5.00 Very Low Very Low Very Low
nMDA receptor antagonist 1 5.00 Very Low Very Low Very Low
gABA 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Poisoning 2 71.92 Quite High
Paralysis 7 57.48 Quite High
Anaerobic Bacterial Infections 22 50.00 Quite Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Infection 4 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Autolysis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indeed, in hippocampal neurons, as well as in inhibitory spinal cord neurons that are the physiological targets of TeNT, we observed markedly enhanced cleavage of TeNT's substrate, syb II, under conditions that stimulate SV exo- and endocytosis.
Positive_regulation (enhanced) of Protein_catabolism (cleavage) of syb II in neurons associated with spinal cord
1) Confidence 0.16 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2991259 Disease Relevance 0.13 Pain Relevance 0.13

General Comments

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