INT346407

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Tesc, Sv2a) transport (Sv2a) transmembrane transporter activity (Sv2a)
endoplasmic reticulum (Sv2a) plasma membrane (Tesc) nucleus (Tesc)
Anatomy Link Frequency
neurons 2
Tesc (Mus musculus)
Sv2a (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 46 67.20 Quite High
Central nervous system 6 26.16 Quite Low
Neurotransmitter 4 21.20 Low Low
tetrodotoxin 14 5.00 Very Low Very Low Very Low
Action potential 5 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
sodium channel 1 5.00 Very Low Very Low Very Low
nMDA receptor antagonist 1 5.00 Very Low Very Low Very Low
gABA 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anaerobic Bacterial Infections 22 50.00 Quite Low
Paralysis 7 17.88 Low Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Infection 4 5.00 Very Low Very Low Very Low
Poisoning 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Autolysis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The loss of PSGs might dramatically reduce the affinity of TeNT for the peripheral receptor, relative to SV2, so TeNT can be released from the MN and target inhibitory neurons after transcytosis.
Spec (might) Negative_regulation (reduce) of TeNT Spec (might) Binding (affinity) of SV2 in neurons
1) Confidence 0.02 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2991259 Disease Relevance 0 Pain Relevance 0.03

General Comments

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