INT346431

Context Info Confidence 0.01 First Reported 2010 Last Reported 2010 Negated 1 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.17 Pain Relevance 0

isomerase activity (PPIG) protein folding (PPIG) nucleoplasm (PPIG) nucleolus (PPIG) nucleus (PPIG) cytoplasm (PPIG)

Anatomy Link Frequency ECs 2 PPIG (Homo sapiens)

Pain Link Frequency Relevance Heat Bile 1 30.20 Inflammation 9 5.00 cytokine 2 5.00 agonist 2 5.00 cINOD 2 5.00 Inflammatory mediators 1 5.00 Inflammatory response 1 5.00

Disease Link Frequency Relevance Heat Leukemia 1 84.88 Apoptosis 1 83.20 Death 19 48.24 Hyperplasia 3 30.56 Disorder Of Lipid Metabolism 2 20.80 Cancer 8 16.00 Colon Cancer 15 5.00 INFLAMMATION 12 5.00 Osteoarthritis 2 5.00 Metastasis 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Likewise, the induction of cyclooxygenase-2 (Cox-2, prostaglandin G-H synthase-2) expression in cultured bovine coronary artery endothelial cells (ECs) does not depend on the activity of Cytochrome P450 (CYP), which are enzymes essential for cholesterol and isoprenoid biosynthesis [15].

Neg (not) Positive_regulation (depend) of Neg (not) Regulation (depend) of CYP in ECs

1) Confidence 0.01 Published 2010 Journal J Angiogenes Res Section Body Doc Link PMC2991284 Disease Relevance 0.17 Pain Relevance 0

General Comments

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