INT346457

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IRF3) nucleoplasm (IRF3) plasma membrane (IRF3)
nucleus (IRF3) DNA binding (IRF3) cytoplasm (IRF3)
IRF3 (Homo sapiens)
IFNA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 20 53.84 Quite High
chemokine 2 53.04 Quite High
Inflammation 15 50.00 Quite Low
fibrosis 7 49.04 Quite Low
adenocard 1 34.00 Quite Low
Inflammatory response 1 21.60 Low Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatitis C Virus Infection 72 97.28 Very High Very High Very High
Infection 20 75.52 Quite High
Disorder Of Lipid Metabolism 2 56.52 Quite High
Hepatocellular Cancer 76 50.80 Quite High
INFLAMMATION 17 50.00 Quite Low
Cirrhosis 28 49.04 Quite Low
Hepatitis B Virus Infection 10 46.04 Quite Low
Liver Cancer 11 40.04 Quite Low
Hepatitis 10 22.04 Low Low
Cancer 17 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These two kinases in turn phosphorylate the interferon regulator factor-3 (IRF-3) that activates the IFN-?
IRF-3 Positive_regulation (activates) of IFN
1) Confidence 0.03 Published 2010 Journal J Transl Med Section Body Doc Link PMC2991329 Disease Relevance 0.56 Pain Relevance 0.05

General Comments

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