INT346494

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.63
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (RXRA) small molecule metabolic process (RXRA) aging (RXRA)
nucleus (RXRA) enzyme binding (RXRA) DNA binding (RXRA)
RXRA (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 15 50.00 Quite Low
cINOD 1 47.40 Quite Low
COX-2 inhibitor 1 44.80 Quite Low
cytokine 20 5.00 Very Low Very Low Very Low
fibrosis 7 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatocellular Cancer 76 99.24 Very High Very High Very High
Cancer 17 78.84 Quite High
Apoptosis 5 75.76 Quite High
Liver Cancer 11 65.28 Quite High
Hepatitis C Virus Infection 72 50.00 Quite Low
INFLAMMATION 17 50.00 Quite Low
Cirrhosis 28 40.08 Quite Low
Stress 4 34.48 Quite Low
Infection 20 5.00 Very Low Very Low Very Low
Hepatitis 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, the combination of 9-cis-retinoic acid (9cRA) plus trastuzumab resulted to inhibit the activation of HER2 and its downstream signaling pathways, subsequently inhibiting the phosphorylation of RXR alpha and the growth of HCC cells [76].


Phosphorylation (phosphorylation) of RXR alpha associated with hepatocellular cancer
1) Confidence 0.01 Published 2010 Journal J Transl Med Section Body Doc Link PMC2991329 Disease Relevance 0.63 Pain Relevance 0

General Comments

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