INT346518

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Context Info
Confidence 0.23
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

proteinaceous extracellular matrix (TFIP11) plasma membrane (PTH2R) nucleus (TFIP11)
intracellular (TFIP11) DNA binding (TFIP11) signal transducer activity (PTH2R)
Anatomy Link Frequency
TM3 1
TFIP11 (Homo sapiens)
PTH2R (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 2 87.56 High High
Neuropathic pain 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Sciatic nerve 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Nociception 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Nervous System Injury 1 5.00 Very Low Very Low Very Low
Anxiety Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Positions in PTH2R which have been shown to be directly involved in the discrimination between the PTH and PTHrP for PTH2R; Ile244 (interacts with Leu2 and Ala3 in TIP39 in the model of the complex) in TM3 and Cys397 (matched to Glu12 in TIP39) and Phe400 (in proximity of Ala5 and Ala8 in TIP39) in TM7 are in close contact with the placed ligand [38].
TIP39 Regulation (Positions) of PTH2R in TM3
1) Confidence 0.23 Published 2010 Journal BMC Res Notes Section Body Doc Link PMC2991341 Disease Relevance 0 Pain Relevance 0.04

General Comments

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