INT346544

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Context Info
Confidence 0.47
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.75
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (PTH2R) signal transducer activity (PTH2R)
PTH2R (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuropathic pain 8 93.12 High High
Sciatic nerve 2 65.92 Quite High
antagonist 4 60.88 Quite High
Kinase C 2 51.12 Quite High
agonist 2 35.28 Quite Low
Pain 4 32.96 Quite Low
adenocard 2 11.68 Low Low
Disease Link Frequency Relevance Heat
Stress 4 99.00 Very High Very High Very High
Anxiety Disorder 2 95.88 Very High Very High Very High
Neuropathic Pain 8 93.12 High High
Targeted Disruption 2 84.56 Quite High
Nociception 4 81.76 Quite High
Nervous System Injury 2 65.28 Quite High
Pain 4 32.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Another study has shown that the TIP39 - PTH2R system is activated in response to acoustic stress [21].
Positive_regulation (activated) of PTH2R associated with stress
1) Confidence 0.47 Published 2010 Journal BMC Res Notes Section Body Doc Link PMC2991341 Disease Relevance 0.75 Pain Relevance 0.25
The hypothesis could be tested by the mutation of the Ile5 of PTH to Asp in order to explore if that mutant can fully activate PTH2R.
Positive_regulation (activate) of PTH2R
2) Confidence 0.32 Published 2010 Journal BMC Res Notes Section Body Doc Link PMC2991341 Disease Relevance 0 Pain Relevance 0

General Comments

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