INT346564

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell death (Rraga) Golgi apparatus (Rraga) nucleus (Rraga)
lysosome (Rraga) cytoplasm (Rraga)
Rraga (Mus musculus)
Pain Link Frequency Relevance Heat
Peripheral nervous system 4 34.40 Quite Low
Neuropathic pain 4 7.68 Low Low
peripheral neuropathy 6 5.00 Very Low Very Low Very Low
Spinal cord 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
analgesia 2 5.00 Very Low Very Low Very Low
hypoalgesia 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 6 7.68 Low Low
Fabry Disease 36 5.00 Very Low Very Low Very Low
Disease 22 5.00 Very Low Very Low Very Low
Gauchers Disease 14 5.00 Very Low Very Low Very Low
Nociception 6 5.00 Very Low Very Low Very Low
Peripheral Neuropathy 6 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Cerebrovascular Disease 4 5.00 Very Low Very Low Very Low
Disease Progression 4 5.00 Very Low Very Low Very Low
Heart Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In untreated Fabry patients, uromodulin excretion has been reported as being reduced [32], while we found an increase in the untreated Fabry-Rag mouse model.
Positive_regulation (increase) of Fabry-Rag
1) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2991350 Disease Relevance 0 Pain Relevance 0
Although this progressive increase in latency in the Fabry-Rag was qualitatively similar to that observed in the Fabry model (Figure 3), it was not as dramatic, and did not approach the latency (60 sec) seen in the immunocompetent Fabry mouse.
Positive_regulation (increase) of Fabry-Rag
2) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2991350 Disease Relevance 0 Pain Relevance 0

General Comments

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