INT346569

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Context Info
Confidence 0.30
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.46
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cellular_component (Sh2d1b2)
Sh2d1b2 (Mus musculus)
Pain Link Frequency Relevance Heat
peripheral neuropathy 3 73.80 Quite High
Spinal cord 2 5.00 Very Low Very Low Very Low
Neuropathic pain 2 5.00 Very Low Very Low Very Low
Peripheral nervous system 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
analgesia 1 5.00 Very Low Very Low Very Low
hypoalgesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 11 87.48 High High
Peripheral Neuropathy 3 73.80 Quite High
Fabry Disease 18 60.56 Quite High
Targeted Disruption 2 53.60 Quite High
Gauchers Disease 7 49.76 Quite Low
Diarrhoea 1 11.00 Low Low
Nociception 3 5.00 Very Low Very Low Very Low
Neuropathic Pain 3 5.00 Very Low Very Low Very Low
Cerebrovascular Disease 2 5.00 Very Low Very Low Very Low
Disease Progression 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-gal elicited the production of antibodies against the recombinant human enzyme (that may complicate interpretation of the results), studies that involved the use of ERT were performed using the Fabry-Rag mouse model, which does not generate a humoral response to recombinant human ?
Positive_regulation (performed) of Gene_expression (use) of ERT
1) Confidence 0.30 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2991350 Disease Relevance 0.46 Pain Relevance 0.04

General Comments

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